Rising threats from AntiMicriobial Resistance

Many efforts to reduce AMR have been initiated, are ongoing and have been concluded. However many of these have been proven to be only partially sufficient. In order to succeed, a holistic approach is needed (Communication from the Commission to the European Parliament and the Council – Action plan against the rising threats from Antimicrobial Resistance). AMR is a major European and global societal problem, involving many different sectors e.g. medicine, veterinary

medicine, animal husbandry, agriculture, environment and trade. It cannot be tackled successfully through isolated, sectoral efforts. Food and direct contact with animals may serve as a vehicle for the transmission of AMR from animals to humans emphasizing the link between human and veterinary medicine in line with the “One Health” initiative. The fact that resistance may spread from country to country when people and animals travel or when food, feed and other possible vehicles

of AMR are traded, stresses the need for coordinated efforts across borders. The AMICI network addresses key actions as formulated by the EC, for a successful fight against AMR including the prevention of microbial infections and their spread through the sustainable introduction of AMC and new cleaning.

AMICI aims at being an innovative, out-of-the-box network that will challenge classic approaches in this field, such as new antibiotic development, thereby challenging older concepts and sectoral thinking and pave the way for innovative approaches, such as introduction of AMC and new cleaning.

The participants, representing the entire value chain in healthcare, has the power to introduce new concepts into existing structures in hygiene, microbial resistance and cleaning-disinfection. AMICI has contacted other COST Actions, such as iPromedai, to explore how AMICI can benefit from the experiences and results with respect to combatting device-associated infections and the challenges they face in bringing together clinics, engineering, pharmacology and microbiology. But also to evaluate if and how the work from AMICI can feed into the iPromedai network. Similar efforts have been made with FP7 projects such as PARCIVAL, CuViTo, SelfClean and AMSCOPPER.

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