AMC Posters, Workshops

Emulsion Electrospun Fiber Mats of PCL/PVA/Chitosan and Eugenol aimed for antimicrobial wound healing applications

In recent years, the damaging effects of antimicrobial resistance relating to wound management and infection have driven the ongoing development of composite wound dressing mats containing natural compounds, such as plant extracts and its derivatives.
The present research reports the fabrication of novel electrospun Polycaprolactone (PCL) / Polyvinyl Alcohol (PVA)/ Chitosan (CH) fiber mats loaded with Eugenol (EUG), an essential oil extracted from cloves, known for its therapeutic properties. The electrospun fiber mats were prepared via electrospinning from either water-in-oil (W/O) or oil-in-water (O/W) emulsions, using Nanospider Technology, and characterized using scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), total porosity measurements and contact angle. The in vitro EUG release and in vitro antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa were also evaluated.

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