AMC Posters, Safe-by-Design ...

Agar/ nanosilver composite coatings for prevention of biofilm formation

Bacterial contamination on various surfaces is very common and causes serious problems, particularly on hospital surfaces/furniture and medical devices The formation of biofilms on such surfaces is recognized as the most critical biological contamination due to a difficult removal of microorganisms within the biofilm and their high resistance to different antimicrobial agents. In an attempt to overcome these problems, various strategies have been employed to develop methods that can effectively prevent biofilm formation. These methods usually include application of different antimicrobial coatings or biocides on the surfaces which make them resistant to bacterial adhesion. Silver nanoparticles (AgNPs) have long been recognized as one of the most effective antimicrobial agent with a broad spectrum of antimicrobial activity. However, surface coatings designed by use of nanosilver only, cannot provide both strong antimicrobial effect and good biocompatibility. To overcome these disadvantages nanosilver can be incorporated into various polymeric materials. In this study, we have prepared agar/AgNPs composite coatings using an environmentally-friendly method, i.e., reduction of AgNO3 in the presence of agar solution.

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